If you are having trouble viewing this email, please click the following link.
http://www.visioncareprofessional.com/emails/OSN/issue_032014.asp


Diagnostics. We want better, more accurate, one-stop-shop methods of determining who has disease, and who does not, for all ocular conditions. However, it is hard for clinicians to incorporate new techniques into routine clinical care. When I ask my students, specifically students in the early years of optometry school, why we measure visual acuity, or perform measurement of IOP, usually I get an answer along the lines of “because it is part of a routine eye exam.” So how did the “tests” of “routine eye exam” get determined? And, more importantly, how would a new “test” get added?

In our efforts to screen for ocular conditions, tests that are the most sensitive (able to detect those that have disease) and specific (able to determine those without the disease) are generally those we perform. However, many of our clinical tests in an eye exam are historic, and rather than opt-out, we tend to add on with newer tests. With several new tests related to ocular surface conditions available to the clinician (e.g. TearLab osmolarity, InflammaDry, Sjo), when should we perform these tests? Should they be used to screen for disease in a routine exam, or is the place for these tests an ocular surface specific medically-oriented exam?

If the goal of a test is to screen for and identify early a condition, like dry eye, the place should be a routine exam. If the test provides specific information that can be used to monitor a condition over time or with treatment, the test could be considered as part of a specialty exam. Either way, beyond symptoms, there has not been wide adoption to date in either scenario. Why not? Studies have shown it takes years for health professionals to adopt even one new bit of technology, so what would it take to adopt a screening for dry eye in a routine exam? I am confident that day is imminent, when we screen for ocular surface wellness in the routine exam. Join me in this effort.



Kelly K. Nichols, OD, MPH, PhD
Editor


March 20, 2014
Editor's Commentary
News
New Retaine HPMC Lubricant Eye Drops Available in Multi-Dose Preservative-Free Bottle

Nicox Appoints Pardo as Director of Professional Affairs

TearScience Partners with Cowealth Medical to Introduce Product Line to China

Nicox Launches AdenoPlus and Xailin in Europe

Clinician's Corner: The Future of Dry Eye Diagnostics
Research Update: Commentary on Abstract of the Week
Abstract
Dry Eye 101: Medical Coding & Compliance


Advertisement

Results from last poll:

Besides Ocular Surface News, where do you prefer to get new information about ocular surface disease?

 1. Reading abstracts/papers from places like PubMed
   11%

 2. Attending lectures at meetings
   34%

 3. Reading trade journals like Optometric Management
   40%

 4. Talking to pharmaceutical reps or colleagues
   6%

 5. Viewing video content online
   9%



NEWS

New Retaine HPMC Lubricant Eye Drops Available in Multi-Dose Preservative-Free Bottle
OCuSOFT Inc. introduces Retaine HPMC Lubricant Eye Drops now available in a patented multi-dose, preservative-free delivery system.

Retaine HPMC Lubricant Eye Drops is a preservative-free Hypromellose Ophthalmic Solution (0.3%) that provides immediate relief to soothe dry, irritated eyes by resembling natural tears, according to the company. Utilizing a patented proprietary airless pump system that prevents harmful bacteria from entering the bottle and contaminating the solution, Retaine HPMC enables delivery of multiple sterile doses to the eye without preservatives that can be damaging to the sensitive ocular surface. Most solutions intended for multiple use require the addition of preservatives, but Retaine HPMC has a three month stability after opening with guaranteed sterility.

Retaine HPMC in its multi-dose bottle allows for lower cost of treatment and is only available from OCuSOFT. Retaine HPMC joins a growing line of Retaine brand eye care products which are discounted to practitioners for direct dispensing to the patient. The program serves to not only increase practice revenues but provide added convenience and savings to patients.

For more information, call (800) 233-5469 or visit www.ocusoft.com.

^ Back to top  

 

Nicox Appoints Pardo as Director of Professional Affairs
Nicox Inc., a wholly-owned subsidiary of international ophthalmic company Nicox S.A., appointed Dennis Pardo, OD, MPH, FAAO to the position of Director of Professional Affairs. In this role, Dr. Pardo will partner with established and emergent key opinion leaders to identify and develop preferred practice patterns for Nicox's diagnostic offerings, including Sjö for the early detection of Sjögren's syndrome in dry eye patients and RetnaGene AMD for risk assessment of early or immediate age-related macular degeneration (AMD) progressing to advanced choroidal neovascular disease. Additionally, Dr. Pardo will serve as the primary liaison between Nicox and the Sjögren's Syndrome Foundation, as well as other patient advocacy groups.

Dr. Pardo brings over 17 years of ophthalmic experience to the newly formed position, including time spent in academia, various practice settings, and industry. He is a Doctor of Optometry from The New England College of Optometry, where he also did his Residency in Family Practice/Ocular Disease. He holds a Master's Degree in Public Health/Health Care Management from Yale University and Bachelor of Science degree in Biological Sciences from The State University of New York at Stony Brook. Dr. Pardo is a Fellow of the American Academy of Optometry and serves on its Membership Committee. He is also a member of the American Optometric Association and The Massachusetts Society of Optometrists. Industry experience includes time at Advanced Vision Research, J&J Vision Care/Vistakon, ISTA and Avedro, where he served in numerous executive capacities.

^ Back to top  

 

TearScience Partners with Cowealth Medical to Introduce Product Line to China
TearScience, Inc. has entered into an exclusive partnership agreement with Cowealth Medical to distribute and service its in-office Dry Eye Solution products in China, Taiwan, Hong Kong and Macao. Established in 1997 and headquartered in Shanghai, Cowealth Medical specializes in distributing innovative medical products in the greater China region.

The TearScience in-office Dry Eye Solution includes the LipiView Ocular Surface Interferometerand LipiFlow Thermal Pulsation System along with a simplified implementation plan, effective marketing tools, and proven post-installation procedure support, providing eyecare professionals with a complete dry eye clinical and business franchise.

^ Back to top  

 

Nicox Launches AdenoPlus and Xailin in Europe
Nicox S.A. announced the European launch of Xailin, a new range of tear lubricants for relief of dry eye symptoms, and of AdenoPlus, an in vitro diagnostic medical device to help the differential diagnosis of acute conjunctivitis. Nicox is now promoting and selling the first Xailin products and AdenoPlus through its own sales force in the UK, Italy, Spain and France. Commercial operations in Germany are expected to begin in the second quarter of 2014.

Xailin is a proprietary brand under which Nicox intends to commercialize a range of products for dry eye, starting with the first two products, a multi-dose preservative-free lubricating ointment for night-time relief of dry eye sensations, and a unit-dose preservative-free lubricant that alleviates and soothes dry eye sensations.

The Xailin range will include medical devices developed by Medicom Healthcare, a private UK-based pharmaceutical company specializing in ophthalmics, as per an exclusive supply and distribution agreement signed in March 2013. Nicox will launch the Xailin range of artificial tears in Europe, Middle East and Africa. Other tear lubricants are planned to be launched throughout the year 2014.

^ Back to top

 

CLINICIAN'S CORNER:
THE FUTURE OF DRY EYE DIAGNOSTICS

Guest Columnist: Michael A. Lemp, MD

There has been significant movement forward in our understanding of the roles of symptoms and objective markers in the diagnosis of dry eye disease (DED). While most patients with DED are symptomatic, many have clear objective evidence of DED while not reporting symptoms on standard questionnaires. It may be that the questionnaires don't necessarily capture symptomatology well but other studies suggest that the presence and degree of symptoms is influenced by other factors such as alterations in ocular surface sensory receptors, generalized body pain sensitivity and other central nervous system factors. Diagnosis by symptoms alone is fraught with error and this emphasizes the role of objective markers in diagnosis.

The issue is further complicated by the recent findings that the commonly used objective diagnostic markers (Schirmer, tear breakup time, corneal and conjunctival staining) do not correlate well with each other or with symptoms, particularly in patients with mild-moderate disease and are not very repeatable. This reflects that each test addresses specific effects of the disease occurring at different times and degrees in the development of disease. The variability seen is a result of the loss of homeostatic control of the tear/ ocular surface functional unit—a characteristic feature of DED. Most of the tests, however, become more consistent in more severe disease when all aspects of the ocular surface system break down. So what is a clinician to do?

In evaluating tear diagnostics, ask the following questions:

  • Is it specific for DED?
  • Is it repeatable?
  • Is it quantitative?
  • Does is reflect disease over the entire spectrum?
  • Is it a marker for only one subtype of DED e.g. aqueous-tear deficiency or evaporative dry eye or is it a global measure of disease?
At present, tear osmolarity has been shown to meet these requirements and is a global marker of DED. It does, however, not distinguish between subtypes of disease and additional evaluation for subtyping is necessary. Other recent markers, such as InflammaDry which measures MMP-9, is a semi-quantitative test of inflammation and tissue remodeling, not DED specifically. A positive test is suggestive of significant inflammation, which may influence treatment choices. Future developments include the search for specific cytokines or groups thereof which may identify DED subtypes, more objective measures of tear instability, and more advanced measures of visual disability. Stay tuned!

^ Back to top


RESEARCH UPDATE:
COMMENTARY ON ABSTRACT OF THE WEEK
Blair Lonsberry, MS, OD, MEd., FAAO

Dry eye disease (DED) has a prevalence ranging from 7.8% to 14.6% in the United States affecting approximately 4.91 million Americans aged 50 years and older. Difficulty exists in determining the exact prevalence due to discrepancies in how DED is defined and diagnostic criteria. The goal of this study was to determine how eyecare providers are treating DED as compared with the published recommendations outlined in the 2007 DEWS report and the AAO Dry Eye PPP publication.

A 17-question online survey invitation was mailed to 400 members of the North Carolina Ophthalmology and Optometry Associations including community optometrists, comprehensive ophthalmologists, and cornea specialists. One hundred eye care providers responded that burning (46.5%) is the most frequent symptom described by patients, followed by foreign body sensation (30.3%) and tearing (17.2%). Artificial tears are the most recommended first-line treatment. Respondents reported high failure rates for both artificial tears and cyclosporine A (Restasis). The most common comorbid conditions in DED include autoimmune diseases such as rheumatoid arthritis and Sjögren's syndrome, anxiety and depression, refractive surgery, smoking, and thyroid disease. A majority of the respondents of this study didn't report their clinical practice as DED specialists, which, likely represents the “average” eye care provider. TBUT and fluorescein stain were the most frequently used clinical tests in assessing dry eye, though the majority respondents relied on patient history as the most common measure of whether therapy was effective, suggesting that current objective tools don't provide the whole clinical picture. Overall, this study revealed that the representative study group of eye care professionals has current practice patterns that largely reflect the recommendations in the DEWS report and AAO PPP document. The paper also points out that current diagnostic tools may not be sensitive to changes in treatment or changes over time, thus the reliance on subjective measures remains central to a dry eye practice



^ Back to top  


ABSTRACT

Perceptions of Dry Eye Disease Management in Current Clinical Practice
Williamson JF, Huynh K, Weaver MA, Davis RM. Eye Contact Lens. 2014 Mar;40(2):111-5.

OBJECTIVE: To assess the perceptions of eyecare providers regarding the clinical management of dry eye.

METHODS: Invitations to complete a 17-question online survey were mailed to 400 members of the North Carolina Ophthalmology and Optometry Associations including community optometrists, comprehensive ophthalmologists, and cornea specialists.

RESULTS: The survey was completed by 100 eyecare providers (25% response rate). Providers reported burning (46.5%) as the most frequent symptom described by patients, followed by foreign body sensation (30.3%) and tearing (17.2%). Most respondents (80.8%) listed artificial tears as the recommended first-line treatment, even though providers reported high failure rates for both artificial tears and cyclosporine A (Restasis). Rheumatoid arthritis, Sjögren syndrome, affective disorders such as anxiety and depression, history of photorefractive surgery, smoking, and thyroid disease were acknowledged as common comorbid conditions.

CONCLUSIONS: The survey provided an informative snapshot into the preferences of eyecare providers concerning the diagnosis and management of dry eye disease. Overall, burning was the most common symptom reported by patients. Providers relied more on patient history in guiding their clinical decisions than objective signs. The survey underscores the incongruence when comparing subjective symptoms with objective signs, thereby highlighting the urgent need for the development of reliable metrics to better quantify dry eye symptoms and also the development of a more sensitive and specific test that can be used as the gold standard to diagnose dry eye.


^ Back to top  

DRY EYE 101: MEDICAL CODING & COMPLIANCE
By John Rumpakis, OD, MBA


Coding Ancillary Dry Eye Diagnostic Procedures
Managing the ocular surface for patients is a very dynamic and exciting area of practice for today's optometrist. New technologies, such as tear film interferometry and other diagnostic tests provide new diagnostic information that just simply wasn't available on a wide scale basis a few years ago. That being said, many practitioners wonder how to properly code for the procedure or even if the diagnostic procedure is separately coded.

In general, many of the traditional diagnostic tests performed for “dry eye” are not separately identified by the CPT or HCPCS and have been considered to be part of the office visit billed when these tests are performed. Schirmer, Phenol Red Thread, TBUT, and Tear Prism Analysis are tests that fall within these parameters.

However, some new technology that is available is separately identified by either a Level III HCPCS code or a new CLIA waived procedure are able to be coded in addition to the office visit.

CPT code 83516, immunoassay for analyte other than infectious agent antibody or infectious agent antigen; qualitative or semiquantitative, multiple step method, is now a CLIA waived test (be sure to use the modifier – QW on each procedure performed) that can be performed in optometrists offices where the practice has a clinical lab designation and a physician with the practice has been registered as a clinical lab director. The current national payment amount for this lab test is $15.52 per eye. The first, perhaps of many, tests of this nature is called InflammaDry by Rapid Pathogen Screening (RPS).

0330T – Tear Film Imaging, Unilateral or Bilateral, with interpretation and report. Keep in mind that this is a temporary use or “tracking code” for tear film interferometry and as such, it needs to be reported to the carrier, but is generally a patient payable test. There are coordinating rules with CPT code 92285 (anterior segment photography) for this code that one needs to be aware of when performing it.

New technology is always exciting when it can be employed within our practices and provides new avenues of providing great patient care. New technology also requires that we keep up with the appropriate recording and reporting mechanisms that are in place for appropriate compliance.


^ Back to top  


Ocular Surface Update | 321 Norristown Road, Suite 150, Ambler, PA 19002

If you prefer not to receive e-mail from us, please use the following link to remove your e-mail address from our list: Unsubscribe

This message was transmitted by PentaVision LLC | 321 Norristown Road, Suite 150, Ambler, PA 19002 | 215-646-8700

View Our Privacy Policy | Contact Us - Please do not reply to this e-mail message.

Please make sure our e-mail messages don't get marked as spam by adding visioncareprofessionalemail.com to your "approved senders" list.